Research at the Angiogenesis Laboratory Amsterdam
In the process of cancer angiogenesis is a prerequisite for a tumor to
grow beyond a certain size and allow metastasis formation. Over the last
years it has become evident that inhibition of angiogenesis or blockade
of the tumor blood supply are promising tools for treatment of cancer.
The research of the
Angiogenesis Laboratory Amsterdam is aimed to unravel fundamental processes and
mechanisms of angiogenesis and vascular development using molecular and cell biological
techniques. The acquired knowledge is used to develop new diagnostic tools and treatment
modalities for clinical applications.
research is structured in the following research lines:
I: Target and drug discovery
II: Mechanisms of resistance
III: Combination therapies
IV: Personalized treatment strategies